Translation and validation of the Chinese version of the MD Anderson symptom inventory for measuring perioperative symptom burden in patients with gynecologic cancer

Abstract Background Gynecologic cancers are among the most prevalent malignancies in China. Cervical and uterine cancer respectively account for sixth eighth highest incidence of Chinese women. Abdominal surgery is one important treatment methods gynecological tumors. However, tumor- surgery-related symptom burden not well studied owing to a lack standardized validated assessment tool population. The study aimed translate validate MD Anderson Symptom Inventory measuring perioperative gynecologic patients (MDASI-PeriOp-GYN) examine utility version MDASI-PeriOp-GYN. Methods MDASI-PeriOp-GYN was translated stepwise manner. First, two native speakers independently 9 PeriOp-GYN items. Then nine items were back into English by different bilingual translators. After discussion revision, four translators reached an agreement. Finally, finalized administered women with three common types (cervical, ovarian, endometrial cancers) recruited from oncology department Sichuan Cancer Hospital & Institute between July October 2019. reliability validity assessed. Results Overall, 324 enrolled. Cronbach’s ? values 0.826 0.735 severity interference scales, respectively. Test–retest 0.885, 0.873, 0.914 severity, PeriOp-GYN, scales. Significant correlations found MDASI-PeriOp-GYN-C EORTC QLQ-C30 along QLQ-OV28 module (? 0.608–0.871, P < 0.001). Known-group supported significant differences scores scales grouped time intervals, type, functional status (all 0.01). Conclusions valid reliable symptoms undergoing cancers. could be used clinical practice trials instantly gather patients’ health quality life data.